DETROIT — A perfect storm of an upper body workout, too many pitches while warming up in an inning that wouldn’t end, previous shoulder issues and the Mariners’ desire to have a bullpen start Saturday in Toronto sent right-handed reliever Brandon Brennan back to the 10-day injured list today with shoulder inflammation.

“After he played catch yesterday, he felt fatigued and didn’t feel quite right,” manager Scott Servais. “With where we are at coming up on our schedule with a couple of games with an opener and a bullpen day, we really need all of our pieces functioning. He probably needs three or four days down to do nothing and we aren’t in a position to really afford that.”

The first of what is expected to be many prospects to join the team at the end of the season arrived at Comerica Park to take his place on the roster.

Hard-throwing left-hander Taylor Guilbeau, who was one of three pitchers acquired at the MLB trade deadline from the Nationals in exchange for Roenis Elias and Hunter Strickland, had his minor league contract selected and was added to the 40-man and active roster.

When he steps on the mound, Guilbeau, 26, will be making his big league debut. He will be the 62nd player and the 40th pitcher used by the Mariners this season. The record of players used 64 by the 2014 Rangers. The 2017 Mariners also used 40 pitchers.

Guilbeau has been pitching for Class AAA Tacoma since being acquired. He’s got 1.80 ERA with five strikeouts and two walks in five innings pitched over five appearances. He’s rated as the No. 22 prospect in the Mariners organization by MLB Pipeline.

He had an interesting Wednesday in terms of travel. He flew with Class AAA Tacoma out of New Orleans through Denver and into Sea-Tac. When the team landed, manager Daren Brown approached him in the airport.

“He asked me if I slept on the flight,” Guilbeau said. “I told him, ‘Nah, I can’t really sleep good on flights.’ And he said, ‘Well maybe you’ll sleep better on this next one cause you are going to the big leagues.’”

Guilbeau took the redeye out of Sea-Tac at 9:40 p.m. and arrived in Detroit at 5 a.m. this morning.

“I got about two hours of sleep in the clubhouse and I’m ready to go,” he said. “I’ve been dreaming about this my whole life.”

Brennan pitched in three games after returning from the injured list on Aug. 6. He missed 42 games already this season with a shoulder strain. He exited his appearance on Tuesday night after throwing just two pitches and feeling fatigue in his shoulder. Brennan had worked out earlier in the day, threw before the game and then threw 30 pitches in the bullpen while waiting to come into the game

“They need as many fresh arms as possible and since I need a couple of days, it’s just bad timing for me,” he said.

Brennan thinks he should be ready to return when the 10-day minimum is reached. This isn’t like the shoulder strain that kept him out over a month.

“This is nowhere near as bad,” he said. “The first time I really had no idea what it was because it was kind of stemming from my back to my lat to my shoulder. My whole body was kind of fatigue on the right side in general whereas right now I have it isolated. Today it feels way better than it feels two days ago.”

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